Disclaimer: This article is translated with the assistance of AI.
Collagen is a type of protein that makes up 30% of the protein in the human body. Collagen is primarily composed of the amino acids glycine, proline, and hydroxyproline, and is the most abundant structural protein in animal bodies [1]. Structural proteins are proteins that form the structure or framework of cells and tissues. There are now 28 types of collagen known through scientific research! Among them, Type I collagen accounts for the highest proportion in the human body, up to 90% [2].
Collagen is found in connective tissues, skin, tendons, bones, and cartilage. It provides structural support to tissues and plays an important role in cellular processes, including [3]:
Our bodies have a connective tissue called fibroblasts, which are responsible for producing and maintaining collagen levels. However, as we age, our body’s collagen becomes fragmented, and fibroblast function is impaired, leading to a slowdown in collagen production [4]. This series of changes, combined with the loss of elastin, results in signs of aging such as sagging skin and wrinkles!
Although there are 28 types of collagen known through scientific research, we will introduce the 6 most common types today:
| Type | Function |
| Type I Collagen | Helps form body tissues, aids in wound healing, and provides sufficient support for the skin. It is very important for weight management, maintaining health, and for the general beauty benefits people seek. |
| Type II Collagen | Mainly found in cartilage tissue. |
| Type III Collagen | Similar in structure to Type I collagen and often co-exists with it. It can provide tissue firmness and smoothness, and is also related to the formation of various parts of the body. |
| Type IV Collagen | Commonly found in tissue spaces, it provides cushioning and lubrication. It not only aids in smooth movement but also offers protection to the body. |
| Type V Collagen | Helps Type I and Type III collagen function, so it often appears with both. It is commonly found on the surface of tissues, such as hair and gum tissue. |
| Type X Collagen | Commonly found in tissues around bone joints, it helps maintain health. |
As we age, the body’s collagen synthesis gradually decreases, while the rate of collagen breakdown accelerates. This leads to a gradual reduction in collagen content in tissues, particularly in the skin, joints, and bones.
Lifestyle also affects collagen levels. Factors like prolonged sun exposure, smoking, alcohol consumption, and poor nutrition can negatively impact collagen synthesis and breakdown, leading to collagen loss.
Certain illnesses and medications can also affect collagen levels. Conditions like osteoporosis, arthritis, diabetes, and long-term use of steroids can lead to collagen loss.
Consuming too many refined carbohydrates and sugars can lead to glycation (also known as the Maillard Reaction) in the body. Glycation is a process where excess sugar in the body reacts with proteins, forming advanced glycation end products (AGEs). AGEs accumulate in the body and are difficult to metabolize. This glycation process damages proteins essential for various body parts, and the resulting AGEs can cause wrinkles, loss of elasticity, and sagging in the face.
Supplementing with Vitamin C is a very effective method. Collagen is synthesized into a helical structure (a three-dimensional molecular structure) from three polypeptide chains containing amino acids. Vitamin C hydroxylates proline and lysine in these polypeptide chains, promoting collagen synthesis. Therefore, adequate Vitamin C intake is crucial [7]! If you want to get enough Vitamin C from fruits, you can choose guava, kiwi, or other berries and citrus fruits.
Collagen is a type of protein. Once it enters the body, it is broken down by enzymes into amino acids, the smallest units of protein. So, even if we eat foods rich in collagen, they won’t exist in our bodies as collagen but will be dismantled. Therefore, the effect of directly supplementing collagen through food is relatively weak.
In fact, as long as you maintain an intake of high-quality protein (to provide amino acid building blocks) and fruits and vegetables (to provide Vitamin C), you don’t need to worry too much about collagen synthesis! Nevertheless, we’d still like to share some common food choices for collagen supplementation!
While research this year suggests bone broth isn’t the most effective way to supplement collagen, it remains the most popular choice. Beef broth contains Type I collagen, beneficial for skin, and chicken broth contains Type II collagen, which supports joint function. Made from bones and connective tissues, bone broth is rich in calcium, magnesium , phosphorus, collagen, glucosamine, chondroitin, amino acids, and many other nutrients.
Fish and shellfish have bones and ligaments made of collagen. A 2022 study indicated that marine collagen is one of the most easily absorbed forms of collagen [5]. However, it’s important to note that while we can obtain marine collagen from fish and shellfish, the highest concentrations are found in the heads, scales, and eyeballs of marine animals. Therefore, consuming only the flesh might not be as effective.
Although eggs don’t contain connective tissues like other meats, egg whites are rich in proline, an amino acid essential for collagen production. Thus, consuming eggs can indeed have positive effects on our bodies [6].
You’ll find plenty of collagen supplements on the market, such as collagen jellies, powders, and drinks. It’s advisable to carefully check the product’s ingredients and dosage before purchasing. If you have any questions about collagen supplements, it’s best to consult a professional.
Since collagen is primarily derived from animal proteins, individuals with allergies to animal proteins (such as fish, shellfish, eggs, etc.) must be cautious when consuming collagen supplements and foods rich in collagen.
It is generally recommended to take collagen in the morning to maximize absorption.
Collagen is a type of protein. Once ingested, it’s broken down by enzymes in the body into amino acids, the smallest units of protein. Therefore, even if we consume foods rich in collagen, they don’t exist in our bodies as collagen but are broken down. Ligaments, cartilage, and other connective tissues in animals are rich in collagen, so these parts naturally have higher collagen content. This is why pig trotters, pork skin, and fish skin are often mentioned when discussing collagen supplementation.
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