Health Glossary

Relationship between SGPT and ALT

Serum glutamic pyruvic transaminase (SGPT), is an enzyme that is normally present in liver and heart cells. SGPT is released into blood when the liver or heart are damaged. It is also called Alanine Aminotransferase (ALT).
Author Dr. Jacky Lio
Date 2021-07-16
Updated on 2021-07-21
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Variation in the normal ranges of ALT/SGPTConditions and Diseases caused by increased SGPT levelsPossible associated conditions of an increased levels of SGPTHow can I maintain a healthy level of SGPT?

Variation in the normal ranges of ALT/SGPT

Normal ranges vary as below:

Males 10-30 units/L
Females 9-25 units/L

Conditions and Diseases caused by increased SGPT levels

  • Drinking excess of alcohol
  • Acute viral hepatitis A and B
  • Celiac disease (Autoimmune disorder in which people can’t eat gluten because it will damage their small intestine)
  • Heart attack
  • Diabetes
  • Obesity
  • Hepatitis C
  • Glandular fever caused by Epstein-Barr virus
  • Gallbladder inflammation (medically termed as Cholecystitis)

Possible associated conditions of an increased levels of SGPT

SGPT 1.5 to 8 times more than the normal level seen in:

  • Early, late and subclinical hepatitis.
  • Chronic hepatitis.
  • Alcoholic hepatitis.
  • Chemical hepatitis.
  • Liver necrosis.
  • Rye’s syndrome ( a rare condition that causes swelling in the liver and brain).
  • Cholangitis (inflammation of the bile ducts).
  • Hemochromatosis (genetic disorder in which the body stores too much Iron).

SGPT >8 to 10 times more than the normal value seen in:

  • Mostly in acute viral hepatitis.

SGPT >30 times more than the normal value is seen in:

  • Drug toxicity like acetaminophen in alcoholics and malnourished people.

How can I maintain a healthy level of SGPT?

  1. Increase Vitamin D in your diet
    Vitamin D helps in preventing damage to your liver and reducing SGPT levels. Oranges, soy milk, mushrooms, apples, eggs, fortified cereals, tofu, dairy products, cod liver oil, oysters and green leafy vegetables are good sources of vitamin D.
  2. Eat nutrient-rich food
    Organic, plant-based diet is the best for your liver as it helps in its functioning. Avoid consuming too much salt and sodium-rich foods.
  3. Eat more vegetables & fruits
    Fruits and vegetables that are high in antioxidants, like kiwi, pomegranate, papaya, carrot, spinach, bell pepper are good for your liver’s health.
  4. Avoid deep fried & junk foods
  5. Restrict alcoholic beverages & quit smoking
    Alcohol is the most harmful thing for the liver. Consuming nicotine in any form can absorb toxins like nicotine and ammonia into your blood. Liver has a tough time filtering them, and thus becoming weak.
  6. Don’t self medicate
    Metabolizing drugs is too much work for the liver, hence having medicines not prescribed by a qualified physician can do more harm than good.
  7. Exercise regularly
    Regular exercise is imperative for maintaining a healthy liver. It reduces the stress on your liver and increases your energy levels. Exercise also aids in preventing obesity which is a risk factor for liver diseases.
  8. Go for regular preventive health checkups in particular, the liver tests.
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